Important:

Psilocybin truffles are psychoactive substances that can significantly alter perception, cognition, and emotional states. Participation in a psilocybin ceremony is not suitable for everyone.

This document outlines the main contraindications—situations where it may be unsafe or inappropriate to take psilocybin truffles.

The intention is to support your wellbeing and help you make an informed, responsible, self-honouring choice.

If you’re unsure about anything in this document, please consult a medical doctor, your mental health professional, or speak with me directly.

1. Mental Health Contraindications

Psilocybin is not recommended for people who currently have, or have a past history of:

Psychosis-related conditions

• Schizophrenia

• Schizoaffective disorder

• Bipolar disorder type I (especially with manic or psychotic episodes)

• Psychotic depression

• Delusional disorders

• Any previous psychotic episode (including substance-induced)

Other significant psychiatric conditions

• Borderline personality disorder (depending on stability)

• Severe or unstable PTSD

• Severe dissociative disorders

• Severe anxiety disorders with high risk of panic/destabilisation

Current mental health instability

• Suicidal thoughts or recent suicide attempt

• Self-harm behaviour within the past year

• Psychiatric hospitalisation within the past year

• Active addiction unless in stable recovery and medically supported

2. Physical Health Contraindications

Because psilocybin can affect the heart, nervous system, and hormonal balance, the following conditions can make participation unsafe:

Cardiovascular conditions

• Heart disease, arrhythmias

• Uncontrolled high blood pressure

• Previous stroke or TIA

Neurological conditions

• Epilepsy or history of seizures

• Significant brain injuries

• Neurodegenerative conditions (case-by-case)

Other serious medical conditions

• Severe liver or kidney disease

• Unstable endocrine disorders

• Any condition where emotional or physiological stress is medically unsafe

3. Medication Contraindications

Some medications can create dangerous interactions with psilocybin or reduce its effectiveness.
If you take any medication, please read this section carefully.

Medications that should not be combined with psilocybin

• • SSRIs (e.g., sertraline, fluoxetine, escitalopram, citalopram)

  • SNRIs (e.g., venlafaxine, duloxetine)

  • MAOIs (e.g., moclobemide, phenelzine)

  • Tricyclic antidepressants

  • Antipsychotics (e.g., olanzapine, quetiapine, aripiprazole)

  • Lithium (strictly contraindicated—seizure risk)

  • Benzodiazepines

  • Stimulants (Ritalin, Adderall, etc.)

  • Opioids

  • Anti-seizure medications

  • Triptan migraine medications

• Any serotonergic medication

Medications requiring case-by-case assessment

• Blood pressure medications

• Beta blockers

• Hormonal treatments affecting mood

• Sleep medications

• Any drug affecting serotonin, dopamine, or nervous system regulation

• Modafinil / armodafinil

• Parkinson’s medications (e.g., L-Dopa)

• Antihistamines (sedating and non-sedating)

• Herbal supplements affecting neurotransmitters (St. John’s Wort, 5-HTP, SAMe, Rhodiola, Kava, Yohimbe)

If you take any regular medication—even if it seems minor—it is essential to check whether it interacts with psilocybin.
Please consult your doctor or ask me for guidance.

4. Pregnancy, Fertility & Breastfeeding

Psilocybin truffles are not suitable for:

• Pregnancy (any stage)

• Breastfeeding

• Those actively trying to conceive (recommended abstinence for 1–2 months beforehand)

This is due to the emotional intensity and physiological activation that can occur during a journey.

5. Psychological Readiness & Situational Factors

Even if you are physically healthy, it may not be the right timing if you are currently experiencing:

• Acute emotional crisis (bereavement, breakup, major shock)

• Extremely high stress levels

• Severe sleep deprivation

• Intoxication or substance use

• Instability in life circumstances that makes deep inner work unsafe

Honouring your timing is essential.

6. Substance Use Considerations

Please abstain from:

• Alcohol for at least 48–72 hours

• Cannabis for 24–48 hours

• Stimulants for 72 hours

• Psychedelics for 2 weeks

Active addiction is a contraindication unless you are in stable recovery and supported by a professional.

7. Other Conditions to Be Mindful Of

Not necessarily absolute contraindications, but important to consider:

• History of fainting

• Blood sugar instability

• Severe asthma

• Chronic migraines

• Chronic pain conditions

• Autoimmune disorders

• Trauma related to spiritual/psychedelic practices

If unsure, please ask.

8. Voluntary Disclosure (Netherlands Legal Compliance)

Under Dutch and EU privacy laws (including GDPR), we cannot legally require you to share medical or psychological information.
However, your safety is very important, and psilocybin truffles can interact strongly with certain health conditions and medications.

For this reason, you are strongly encouraged to:

• Review the contraindications carefully

• Consult your doctor or mental health professional if anything applies to you

• Voluntarily share any information that might be relevant to your safety

• Speak with me beforehand if you have questions or feel unsure

Any information voluntarily shared is treated confidentially and only used to support your wellbeing.

If someone chooses not to disclose a relevant condition or medication, and it becomes clear that participation may be unsafe, I reserve the right to decline or halt their involvement in the ceremony to protect both them and the group.

By registering, you acknowledge that:

• You take responsibility for ensuring you have no contraindications

• You will seek medical advice if you are unsure about any medication or condition

• You will voluntarily disclose anything that may affect your safety

• You understand that psilocybin can interact powerfully with certain medications and mental health conditions

This clause respects Dutch law while supporting safe, responsible participation.

 I have read the contraindications